Author(s)

Shahid Rashid, MS Ankita Sharma, MR KHUSHI RAM SHARMA

  • Manuscript ID: 120883
  • Volume 2, Issue 6, Jun 2026
  • Pages: 2089–2096

Subject Area: Other

Abstract

Background:Chronic diarrhea affects approximately 4-5% of adults globally and is associated with significant fluid and electrolyte losses. Electrolyte imbalances, particularly hyponatremia, hypokalemia, and metabolic acidosis, represent critical complications contributing to morbidity and mortality.

Objective:This study aimed to evaluate the prevalence and patterns of serum electrolyte imbalances in patients presenting with chronic diarrhea and assess relationships between demographic factors, duration of illness, and severity of electrolyte disturbances.

Methods:A hospital-based cross-sectional study enrolled 150 adult patients with chronic diarrhea lasting more than four weeks. Serum levels of sodium, potassium, chloride, and bicarbonate were measured. Data were analyzed using SPSS version 26.0 with descriptive statistics and chi-square tests.

Results:Electrolyte disturbances were present in 112 patients (74.7%). Hyponatremia was most common (41.3%), followed by hypokalemia (36.0%), metabolic acidosis (29.3%), and hypochloremia (26.0%). Significant associations were found between diarrhea duration and electrolyte abnormality severity (p < 0.05).

Conclusion:Electrolyte imbalances are highly prevalent among patients with chronic diarrhea. Routine monitoring of serum electrolytes is essential for timely intervention and prevention of complications.

Keywords
Chronic diarrheaelectrolyte imbalancehyponatremiahypokalemiametabolic acidosisgastrointestinal disorders