Author(s)
Mr. Abhishek J. Ware, Mr. Shubham Vaidya
- Manuscript ID: 120593
- Volume 2, Issue 6, May 2026
- Pages: 65–91
Subject Area: Pharmaceutical Science and Pharmacology
Abstract
Skin ageing is a universal, inevitable, and multidimensional biological process that significantly impacts the physical appearance, psychological wellbeing, and quality of life of individuals worldwide. The global anti-ageing skincare market, valued at over USD 60 billion and growing at a compound annual growth rate of approximately 5–7%, reflects the enormous personal and commercial significance of skin ageing as a cosmetic concern and public health issue. The visible signs of skin ageing — wrinkles, fine lines, hyperpigmentation, skin laxity, dullness, and uneven texture — are driven by two interconnected processes: intrinsic chronological ageing, which is determined by genetic programming and inevitable cellular senescence, and extrinsic photoageing, which is caused primarily by chronic ultraviolet radiation exposure and results in up to 80% of visible facial ageing changes.
The growing consumer demand for natural, plant-derived, and scientifically validated anti-ageing cosmeceutical products has led to intense scientific interest in identifying and formulating effective botanical anti-ageing actives as alternatives or complements to synthetic retinoids, alpha-hydroxy acids, and UV-filtering chemicals. Amla — the fruit of Emblica officinalis Gaertn. (Family: Phyllanthaceae), commonly known as the Indian Gooseberry — stands as one of the most scientifically compelling and pharmacologically comprehensive natural anti-ageing ingredients available in the Indian botanical pharmacopoeia, having been used in Ayurvedic medicine as a rasayana (rejuvenating tonic) for skin vitality and longevity for more than 5,000 years.